A Statistical Design for Testing Transgenerational Genomic Imprinting in Natural Human Populations

A Statistical Design for Testing Transgenerational Genomic Imprinting in Natural Human Populations

Genomic imprinting is a phenomenon in which the same allele is expressed differently, depending on its parental origin. Such a phenomenon, also called the parent-of-origin effect, has been recognized to play a pivotal role in embryological development and pathogenesis in many species. Here we propose a statistical design for detecting imprinted loci that control quantitative traits based on a r...

Genomic Imprinting in Human Placenta

Luca Lambertini1,2, Men-Jean Lee3, Carmen J. Marsit4 and Jia Chen1,5,6 1Department of Preventive Medicine, Mount Sinai School of Medicine, New York, 2Department of Obstetrics, Gynecology and Reproductive Science, Mount Sinai School of Medicine, New York, 3Department of Obstetrics and Gynecology, Indiana University-Purdue University, Indianapolis, 4Department of Pharmacology and Toxicology, Dart...

Genomic Imprinting and Human Reproduction

A Model for Transgenerational Imprinting Variation in Complex Traits

Despite the fact that genetic imprinting, i.e., differential expression of the same allele due to its different parental origins, plays a pivotal role in controlling complex traits or diseases, the origin, action and transmission mode of imprinted genes have still remained largely unexplored. We present a new strategy for studying these properties of genetic imprinting with a two-stage reciproc...

investigating the integration of translation technologies into translation programs in iranian universities: basis for a syllabus design in translation technology

today, information technology and computers are indispensable tools of any profession and translation technologies have become an indispensable part of translator’s workstation. with the increasing demands for high productivity and speed as well as consistency and with the rise of new demands for translation and localization, it is necessary for translators to be familiar with market demands an...